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FAN Hongqiang, ZHANG Shuai, WAN Hongdan. Optical sensor for low concentration blood glucose detection based on liquid-core MTC[J]. LASER TECHNOLOGY, 2021, 45(4): 448-455. DOI: 10.7510/jgjs.issn.1001-3806.2021.04.007
Citation: FAN Hongqiang, ZHANG Shuai, WAN Hongdan. Optical sensor for low concentration blood glucose detection based on liquid-core MTC[J]. LASER TECHNOLOGY, 2021, 45(4): 448-455. DOI: 10.7510/jgjs.issn.1001-3806.2021.04.007
shu

Optical sensor for low concentration blood glucose detection based on liquid-core MTC

  • 1.

    SWAT School, Nanjing Forest Police College, Nanjing 210023, China

  • 2.

    College of Electronic and Optical Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210023, China

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  • Received Date: August 16, 2020
  • Revised Date: October 19, 2020
  • Published Date: July 24, 2021
    Graphical Abstract
    • Abstract
  • In order to achieve blood glucose concentration detection with ultra-low sample volume and high sensitivity, the influence of the wall thickness and diameter of liquid-core microtube cavity(MTC) on whispery gallery mode(WGM) resonance property was analyzed based on finite-difference time-domain(FDTD) method. The MTC was fabricated by melt-taping method. High-precision coupling of MTC and tapered fiber and the excitation of WGM resonance spectrum were realized by high-precision electronically controlled displacement platform. The surface functionalization and over-coupling methods of MTC were carried out to improve sensitivity and stability. Theoretical analysis and experimental verification have been carried out. The experimental results show that the linearity and sensitivity of the surface functionalized liquid-core MTC sensor are 0.988 and 0.911pm/(mmol· L-1), respectively. The low-concentration blood glucose optical sensor has high sensitivity and stability. This result is helpful for real-time and rapid monitoring of blood sugar during training of athletes, and for ensuring the safety and durability of sports.
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    • References (21)
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