Experimental study about measurement of optical parameters of biological tissue based on least square support vector machine

In order to achieve non-destructively measurement of optical parameters of biological tissue, optical parameters of tissue simulation phantoms were measured in experiments based on CCD technology and least square support vector machine (LS-SVM). From the experiment, the diffuse reflectance distribution of tissue simulation phantoms was measured. The LS-SVM regression model between the optical parameters and the corresponding diffuse reflectance distribution was founded. The prediction average error of the optical parameters of the tissue simulation phantoms was only 5% under small sample conditions. The results show that combination of CCD measurement technology and LS-SVM can measure the optical parameters of tissue simulation phantom accurately.