Abstract: In order to find a more effective and sensitive waveguide sensor,a new kind of structure of anti-resonant reflecting optical waveguide(ARROW) based on the traditional ARROW is proposed.Its reflectivity and transmitted loss are simulated and its sensitivity is calculated.Comparing with traditional surface homogenous sensing ARROW sensors,as waveguide is directly constructed by the sample and a periodic structure is adopted,the beam is mostly confined in the waveguide and the transmitted loss is effectively deduced,then,the sensitivity is greatly improved.