Abstract: In the adaptive optical systems,the precision of Hartmann-Shack wavefront sensor relies on the centroid detecting accuracy,but the noise in the light spot image lead to centroid detecting error.So the noise should be inhibited before estimating centroid.According to analyzing five kinds of common filtering methods by computer simulation and experiment,the two nonlinear filtering algorithms are showed to be the optimal selection.The study will offer valuable reference in enhancement of the precision of wavefront measurement.