Abstract: The laser-induced cavitation bubble collapse sound waves during the high-power laser and matter interaction in liquid were experimentally investigated.Laser-induced cavitation bubble collapse sound waves at different conditions were measured with a piezoelectric transducer hydrophone in the experiments,and the signals of sound waves were analyzed based on fast Fourier transform.The investigation results showed the frequency varied with the radius of laser-generated bubble,i.e,the bigger the radius,and the lower the frequency.The results are valuable for theoretical and practical research in cavitation noise.