Abstract: Selective laser melting (SLM) is used in medical device manufacturing recently due to the unique capability of fabricating high-complexity structures. With the growing popularity of SLM in medical device manufacturing, this paper mainly reviews the research progress of Ti-6Al-4V fabricated by SLM for surgical medical device applications, including the basic technics of SLM-Ti-6Al-4V fabrication, the achievable mechanical properties, cell compatibility, and some application cases. In addition, we summarizes the underlying problems in the field of medical device manufacturing based on the SLM tethnics. Although the development of SLM formed Ti-6Al-4V is relatively slow in the field of medical application, the existing research and potential indicate that with the continuous intensive research of basic manufacture and the continuous clinical practice, the precise treatment of trauma surgery will undoubtedly become possible.