基于MATLAB的单光阱光镊中光阱力的分析

基金项目:

国家自然科学基金资助项目(60378038);河北省自然科学基金资助项目(602163)

详细信息

The analysis of the optical trap force in a single optical trap based on MATLAB

摘要: 在几何光学近似下,对米氏球状粒子所受轴向光阱力进行了数值计算。仿真结果给出了轴向稳定捕获区域和光阱力与光镊系统主要参数的关系。分析表明,激光束束腰半径越小,势阱越深;相对折射率、激光波长、功率等参数对光阱力也有一定影响。数值仿真为实验中参数的选择提供了依据。
- 光镊 /
- 光学势阱 /
- 光阱力 /
- 数值仿真
Abstract: Under the approximation of geometric optics,the axial force exerted on the Mie microsphere particles is simulated.The capture range and the curves of simulation are shown.The results show that decreasing focus spot radius leads to deeper optical traps and that relative refractive index,laser wavelength and power also have some effect on optical trap,which give some reliance on choosing parameters in experiments.
- optical tweezers /
- optical trap /
- optical trapping forces /
- simulation

[1]	ASHKIN A,DZIEDZIC J M,BJORKHOLM J E et al.Observation of a single-beam gradient force optical trap for dielectrical particles [J].Opt Lett,1986,11:288～290.
[2]	ASHKIN A,SCHUTZE K,DZIEDZIC J M et al.Force generation of organelle transport measured in vivio by an infrared laser trap [J].Nature,1990,348:346～348.
[3]	ASHKIN A.Forces of a single-beam gradiant laser trap on a dielectric sphere in the ray optics regime [J].Biophysical Journal,1992,61:569～582.
[4]	BAKKER S T C,HESSELINK G,GROOTH B G et al.Experimental and thoretical investigations on the vadility of the geometrical optics model for calculating the stability of optical traps [J].Cytometry,1991,12:479～485.
[5]	FELGNER H,MYKKER O,SCHLIWA M.Calibration of lightforces in optical tweezers [J].Appl Opt,1995,34:977～982.
[6]	SIMMONS R M,FINER J T,CHU S et al.Quantitative measurements of force and displance using an optical trap [J].Biophysical Journal,1996,70:1813～1822.
[7]	GU M,KE P C,GAN X S.Trapping force by a high numerical-aperture microscope objective obeying the sine condition [J].Rev Sci Instrum,1997,68:3666～3668.
[8]	GAUTHIER R C,ASHMAN M.Simulated dynamic behaviour ofsingle and multiple spheres in the trap region of focused laser beams [J].Appl Opt,1998,37:6421～6431.
[9]	姚新程,李兆霖,程丙英 et al.双层介质球体所受光作用力的分析与计算 [J].光学学报,2000,20:1305～1310.