Abstract: Laser hardening process and machining process parameters for tablet punch pin have been studied.A 2kW CO2 laser is used to harden the punch pin for a pharmaceutical factory.Through laser hardening,petty martensite has obtained with a depth of 0.7mm.Results show that the working surface of the punch pin hardened by laser has higher hardness and strength,abrasive resistance,impact resistance and longer life.This paper introduces the laser hardening process to improve material organization,reduce stress on variable sections,prevent crack produced in the process of manufacture and improve the combined mechanical performances of the punch pin.