Abstract: In order to explore the dose effect relationship of blue laser dazzle effect, electroretinogram was used to evaluate the dazzle effect of a 456nm semiconductor blue laser on rabbit eyes. The dazzle effect of blue laser and its characteristics were evaluated by the recovery time of electroretinogram b-wave amplitude, the dazzling recovery time curves corresponding to different doses were drawn, and the damage of retina after laser irradiation was observed with fundus camera. The results show that the recovery time of b-wave amplitude of electroretinogram (ERG) is prolonged with the increase of laser irradiation dose, and there is a good linear relationship between the recovery time and the dose. No damage is found in the fundus immediately after irradiation and 24h later. This study will provide reference value for the application of blue laser dazzle.