Abstract: In order to improve the high-temperature oxidation resistance of materials, TiC-TiB2/Fe composite coating was in-situ synthesized by laser cladding. The data of phase, microstructure and oxidation resistance of composite coating were obtained after theoretical analysis and experimental verification. The results indicate that the phases of composite coating are mainly composed of -Fe, TiC, TiB2 and (Fe,Cr)7C3 etc. The fine block-shaped TiC particles and strip-shaped TiB2 disperse on the coating substrate uniformly. The continuous and compact oxidation film is formed on the surface of TiC-TiB2/Fe composite coating after being oxidized isothermally at 600℃ for 60h. The oxidation film consists of fine and spherical oxides such as Fe2O3, FeCr2O4, (Cr,Fe)2O3, rutile TiO2 and Al2O3 and so on, arranged closely. Thermodynamic conditions of oxide formation are satisfied. The oxidation kinetic curve of composite coating at constant temperature of 600℃ is parabolic. The rate of oxidation weight gain is much higher during the initial 10h, and then becomes slower gradually. The oxidation weight gain is 0.75mg/cm2 after being oxidized for 60h. The oxidation resistance of composite coating is 15 times higher than that of semi-steel. The results have some guiding significance to improve the high-temperature oxidation resistance of materials.