Abstract: In order to interpolate these missing data of 3-D measurement quickly and accurately and achieve further comparison study, the estimation method of fast interpolation of 3-D data based on priority was proposed. This algorithm was used to interpolate both the data of simulation experiment and twenty frames vibrating speaker. Compared with other common interpolation algorithm, this new algorithm is time-saving and its result is much better. It can be used to handle large amounts of data of 3-D shape measurement.