Abstract: In order to investigate the stray facula in the in-line digital hologram with an array CCD detector irradiated by short intense laser pulse,variable images were gathered with CCD under laser irradiation or not.Different image grey was analyzed based on the diffraction fringes of the particles and the output electrical signal of the pixel.The stray facula was induced by diffracting dust in the pixels and the abnormal behavior of the reset level due to laser absorption of CCD.Without laser irradiation,the image gathered by CCD was quite abnormal due to the thermal effect and memory effect of CCD.The results showed that the stray facula vanished slowly with the elimination of heat during a long time.Finally,the image gathered by CCD can recover normally and the stray facula vanished completely when the dirty was removed and the time interval of the gathering image was prolonged.