Advanced Search

ISSN1001-3806 CN51-1125/TN Map

Volume 27 Issue 4
Dec.  2013
Article Contents
Turn off MathJax

Citation:

Experimental research of protective effects of dimethylthiourea in the rabbit retina laser injury

  • Received Date: 2002-07-30
    Accepted Date: 2003-01-12
  • Dimethylthriourea(DMTU) is an effective free radical scavenger.Through investigation of histopathological and biochemical changes,we have obseved the effects of DMTU on rabbit retina in laser injury.The results show that photoreceptor cells die mainly of apoptosis in laser-induced retina degeneration and DMTU demonstrate the neropotective effect due to inhibition of lipid peroxidation.
  • 加载中
  • [1]

    Tso M O.Invest Ophthalmol Vis Sci,1989,30(12):2430~2454.
    [2]

    Hafezi F,Marti A,Munz K et al.Exp Eye Res,1997,64(6):963~970.
    [3]

    Organisciak D T,Darrow R M,Jiang Y L et al.Invest Ophthalmol Vis Sci,1992,33(5):1599~1608.
    [4] 陈为享,张惠蓉.中华眼科杂志,1994,30(2) :125~127.

    [5]

    Richter C.FEBS-Lett,1993,325(1~2):104~107.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article views(3284) PDF downloads(537) Cited by()

Proportional views

Experimental research of protective effects of dimethylthiourea in the rabbit retina laser injury

  • 1. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing, 100850;
  • 2. Institute of Hygiene and Environmental Medicine, Academy of Military Medical Sciences, Tianjin, 300050

Abstract: Dimethylthriourea(DMTU) is an effective free radical scavenger.Through investigation of histopathological and biochemical changes,we have obseved the effects of DMTU on rabbit retina in laser injury.The results show that photoreceptor cells die mainly of apoptosis in laser-induced retina degeneration and DMTU demonstrate the neropotective effect due to inhibition of lipid peroxidation.

Reference (5)

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return