Modeling and simulation of light scattering information of blood cell in fluid flow

GUO Yong-cai; ZHANG Xiao-ming

doi:10.7510/jgjs.issn.1001-3806.2013.04.016

In order to obtain accurate light scattering information of red blood cell in the fluid flow, the scattering model of red blood cell in the fluid flow was constructed based on the anomalous diffraction approximation and the oblate ellipsoid. The effect of the variety of body, volume, relative refractive index and orientation angle on the scattering amplitude was studied. The simulation data indicate that the volume and relative refractive index of different red blood cell has the prominent effect on the scattering information at small orientation angles. The model was proved by experiments. This result is helpful for measuring red blood cell fast and accurately and the precise measurement of the cell measurement instrument such as flow cytometer.

Modeling and simulation of light scattering information of blood cell in fluid flow

1. Key Laboratory of Opto-Electronic Technology and Systems of Ministry of Education, Chongqing University, Chongqing 400044, China

Received Date: 2012-08-21

Accepted Date: 2012-10-15

Available Online: 2013-07-25

Abstract: In order to obtain accurate light scattering information of red blood cell in the fluid flow, the scattering model of red blood cell in the fluid flow was constructed based on the anomalous diffraction approximation and the oblate ellipsoid. The effect of the variety of body, volume, relative refractive index and orientation angle on the scattering amplitude was studied. The simulation data indicate that the volume and relative refractive index of different red blood cell has the prominent effect on the scattering information at small orientation angles. The model was proved by experiments. This result is helpful for measuring red blood cell fast and accurately and the precise measurement of the cell measurement instrument such as flow cytometer.

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Reference (18)

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Modeling and simulation of light scattering information of blood cell in fluid flow

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